Written By Steve Koenning, Extension Plant Pathologist and Keith Edmisten, Cotton Extension Specialist, NCSUTarget spot (Corynespora cassicola) has been verified on cotton in Eastern North Carolina, and possibly in South Carolina. The geographic extent of the disease and any varietal resistance to Corynespora are not known at this time. Warm humid conditions favor the development of this disease. Quadris and Headline are strobilurin type fungicides that can be applied to cotton and should provide control for ten days to two weeks. The Efficacy of other fungicides on cotton for control of this disease is not known, but many triazole fungicides have not proved to be very effective against this disease.